TGFβ and PDGF-B signaling blockade inhibits myofibroblast development from both bone marrow-derived and keratocyte-derived precursor cells in vivo

Myofibroblasts, the primary cells associated with corneal stromal haze (opacity), can be derived from both cornea-derived and bone marrow-derived precursor cells. In the present study, the role of TGFβ or PDGF blockage on bone marrow-derived myofibroblast development was investigated using a green f...

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Autors principals: Singh, Vivek, Jaini, Ritika, Torricelli, André A M, Santhiago, Marcony R, Singh, Nirbhai, Ambati, Bala K., Wilson, Steven E
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996053/
https://ncbi.nlm.nih.gov/pubmed/24582892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2014.02.013
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