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Protection of Pyruvate against Glutamate Excitotoxicity Is Mediated by Regulating DAPK1 Protein Complex
The neuroprotective activity of pyruvate has been confirmed in previous in vivo and in vitro studies. Here, we report a novel mechanism that pyruvate prevents SH-SY5Y cells from glutamate excitotoxicity by regulating death-associated protein kinase 1 (DAPK1) protein complex. Our results showed pyruv...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3995922/ https://ncbi.nlm.nih.gov/pubmed/24755839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095777 |
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