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Mutations in BIN1 Associated with Centronuclear Myopathy Disrupt Membrane Remodeling by Affecting Protein Density and Oligomerization

The regulation of membrane shapes is central to many cellular phenomena. Bin/Amphiphysin/Rvs (BAR) domain-containing proteins are key players for membrane remodeling during endocytosis, cell migration, and endosomal sorting. BIN1, which contains an N-BAR domain, is assumed to be essential for biogen...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wu, Tingting, Shi, Zheng, Baumgart, Tobias
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995651/
https://ncbi.nlm.nih.gov/pubmed/24755653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093060
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