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Lactate-H(+) Transport Is a Significant Component of the In Vivo Corneal Endothelial Pump

PURPOSE. To confirm the expression of monocarboxylate transporters (MCT) 1, 2, and 4 in rabbit CE and to test the hypothesis that cellular buffering contributed by HCO(3)(−), NBCe1, and carbonic anhydrase (CA) activity facilitates lactate-H(+) efflux thereby controlling corneal hydration in vivo. ME...

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Bibliographic Details
Main Authors: Nguyen, Tracy T., Bonanno, Joseph A.
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995573/
https://ncbi.nlm.nih.gov/pubmed/22410572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-9475
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