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Hepatic ATGL mediates PPAR-α signaling and fatty acid channeling through an L-FABP independent mechanism
Adipose TG lipase (ATGL) catalyzes the rate-limiting step in TG hydrolysis in most tissues. We have shown that hepatic ATGL preferentially channels hydrolyzed FAs to β-oxidation and induces PPAR-α signaling. Previous studies have suggested that liver FA binding protein (L-FABP) transports FAs from l...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3995459/ https://ncbi.nlm.nih.gov/pubmed/24610891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M039867 |
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