Maintaining end-expiratory transpulmonary pressure prevents worsening of ventilator-induced lung injury caused by chest wall constriction in surfactant-depleted rats

OBJECTIVE: To see whether in acute lung injury (ALI) 1) compression of the lungs caused by thoracoabdominal constriction degrades lung function and worsens ventilator-induced lung injury (VILI), and 2) maintaining end-expiratory transpulmonary pressure (Pl) by increasing positive end-expiratory pres...

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Main Authors: Loring, Stephen H., Pecchiari, Matteo, Valle, Patrizia Della, Monaco, Ario, Gentile, Guendalina, D'Angelo, Edgardo
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995420/
https://ncbi.nlm.nih.gov/pubmed/20890197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e3181fa02b8
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