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Clinical, radiographic and immunogenic effects after 1 year of tocilizumab-based treatment strategies in rheumatoid arthritis: the ACT-RAY study

OBJECTIVE: To assess the 1-year efficacy and safety of a regimen of tocilizumab plus methotrexate or placebo, which was augmented by a treat-to-target strategy from week 24. METHODS: ACT-RAY was a double-blind, 3-year trial. Adults with active rheumatoid arthritis despite methotrexate were randomise...

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Detalhes bibliográficos
Main Authors: Dougados, Maxime, Kissel, Karsten, Conaghan, Philip G, Mola, Emilio Martin, Schett, Georg, Gerli, Roberto, Hansen, Michael Sejer, Amital, Howard, Xavier, Ricardo M, Troum, Orrin, Bernasconi, Corrado, Huizinga, T W J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995223/
https://ncbi.nlm.nih.gov/pubmed/24473673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2013-204761
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