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Poliovirus chimeras replicating under the translational control of genetic elements of hepatitis C virus reveal unusual properties of the internal ribosomal entry site of hepatitis C virus.

Chimeric genomes of poliovirus (PV) have been constructed in which the cognate internal ribosomal entry site (IRES) element was replaced by genetic elements of hepatitis C virus (HCV). Replacement of PV IRES with nt 9-332 of the genotype Ib HCV genome, a sequence comprising all but the first eight r...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Lu, H H, Wimmer, E
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39952/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643645/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.4.1412
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