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Intravenous Magnesium For Pediatric Sickle Cell Vaso-occlusive Crisis: Methodological issues of a randomized controlled trial

BACKGROUND: Multiple recent Sickle Cell Disease studies have been terminated due to poor enrollment. We developed methods to overcome past barriers and utilized these to study the efficacy and safety of intravenous magnesium for vaso-occlusive crisis (VOC). We describe the methods of the Intravenous...

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Bibliographic Details
Main Authors: Badaki-Makun, Oluwakemi, Scott, J. Paul, Panepinto, Julie A., Casper, Charles, Hillery, Cheryl, Dean, J. Michael, Brousseau, David C.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995128/
https://ncbi.nlm.nih.gov/pubmed/24443249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24925
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