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Autonomously Bioluminescent Mammalian Cells for Continuous and Real-time Monitoring of Cytotoxicity

Mammalian cell-based in vitro assays have been widely employed as alternatives to animal testing for toxicological studies but have been limited due to the high monetary and time costs of parallel sample preparation that are necessitated due to the destructive nature of firefly luciferase-based scre...

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Main Authors: Xu, Tingting, Close, Dan M., Webb, James D., Ripp, Steven A., Sayler, Gary S.
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995105/
https://ncbi.nlm.nih.gov/pubmed/24193545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50972
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