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Distribution of genetic polymorphisms of genes encoding drug metabolizing enzymes & drug transporters - a review with Indian perspective

Phase I and II drug metabolizing enzymes (DME) and drug transporters are involved in the absorption, distribution, metabolism as well as elimination of many therapeutic agents, toxins and various pollutants. Presence of genetic polymorphisms in genes encoding these proteins has been associated with...

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Detalhes bibliográficos
Main Authors: Umamaheswaran, Gurusamy, Kumar, Dhakchinamoorthi Krishna, Adithan, Chandrasekaran
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994740/
https://ncbi.nlm.nih.gov/pubmed/24604039
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