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The statistical interpretation of pilot trials: should significance thresholds be reconsidered?

BACKGROUND: In an evaluation of a new health technology, a pilot trial may be undertaken prior to a trial that makes a definitive assessment of benefit. The objective of pilot studies is to provide sufficient evidence that a larger definitive trial can be undertaken and, at times, to provide a preli...

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Detalhes bibliográficos
Main Authors: Lee, Ellen C, Whitehead, Amy L, Jacques, Richard M, Julious, Steven A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994566/
https://ncbi.nlm.nih.gov/pubmed/24650044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2288-14-41
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