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Translation of the Prion Protein mRNA Is Robust in Astrocytes but Does Not Amplify during Reactive Astrocytosis in the Mouse Brain

Prion diseases induce neurodegeneration in specific brain areas for undetermined reasons. A thorough understanding of the localization of the disease-causing molecule, the prion protein (PrP), could inform on this issue but previous studies have generated conflicting conclusions. One of the more int...

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Autors principals: Jackson, Walker S., Krost, Clemens, Borkowski, Andrew W., Kaczmarczyk, Lech
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994155/
https://ncbi.nlm.nih.gov/pubmed/24752288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095958
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