Loss of PINK1 Impairs Stress-Induced Autophagy and Cell Survival

The mitochondrial kinase PINK1 and the ubiquitin ligase Parkin are participating in quality control after CCCP- or ROS-induced mitochondrial damage, and their dysfunction is associated with the development and progression of Parkinson's disease. Furthermore, PINK1 expression is also induced by...

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Bibliografiske detaljer
Main Authors: Parganlija, Dajana, Klinkenberg, Michael, Domínguez-Bautista, Jorge, Hetzel, Miriam, Gispert, Suzana, Chimi, Marthe A., Dröse, Stefan, Mai, Sören, Brandt, Ulrich, Auburger, Georg, Jendrach, Marina
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994056/
https://ncbi.nlm.nih.gov/pubmed/24751806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095288
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