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Preliminary Development of a DNA Aptamer-Magnetic Bead Capture Electrochemiluminescence Sandwich Assay for Brain Natriuretic Peptide

Fifty-two candidate DNA aptamer sequences were selected for binding to the cardiovascular biomarker B-type or brain natriuretic peptide (BNP). Candidate aptamers were screened to rank their relative affinities against BNP by an aptamer-based ELISA-like aptamer microplate assay (ELASA). The highest a...

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Main Authors: Bruno, John G., Richarte, Alicia M., Phillips, Taylor
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993981/
https://ncbi.nlm.nih.gov/pubmed/24764602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.microc.2014.02.003
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