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pH-Dependent Coordination of Pb(2+) to Metallothionein2: Structures and Insight into Lead Detoxification

[Image: see text] Lead is a toxic heavy metal whose detoxification in organisms is mainly carried out by its coordination with some metalloproteins such as metallothioneins (MTs). Two Pb–MT complexes, named as Pb(7)–MT2(I) and Pb(7)–MT2(II), form under neutral and weakly acidic conditions, respectiv...

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Detalhes bibliográficos
Main Authors: He, Yonghui, Liu, Mengmeng, Darabedian, Narek, Liang, Yizeng, Wu, Deyin, Xiang, Juan, Zhou, Feimeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993925/
https://ncbi.nlm.nih.gov/pubmed/24559479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic402452s
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