Identification of a Broad-Spectrum Antiviral Small Molecule against Severe Acute Respiratory Syndrome Coronavirus and Ebola, Hendra, and Nipah Viruses by Using a Novel High-Throughput Screening Assay

Severe acute respiratory syndrome coronavirus (SARS-CoV) and Ebola, Hendra, and Nipah viruses are members of different viral families and are known causative agents of fatal viral diseases. These viruses depend on cathepsin L for entry into their target cells. The viral glycoproteins need to be prim...

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Egile Nagusiak: Elshabrawy, Hatem A., Fan, Jilao, Haddad, Christine S., Ratia, Kiira, Broder, Christopher C., Caffrey, Michael, Prabhakar, Bellur S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Vaccines and Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993759/
https://ncbi.nlm.nih.gov/pubmed/24501399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03050-13
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