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Transcriptional Derepression of the ERVWE1 Locus following Influenza A Virus Infection

Syncytin-1, a fusogenic protein encoded by a human endogenous retrovirus of the W family (HERV-W) element (ERVWE1), is expressed in the syncytiotrophoblast layer of the placenta. This locus is transcriptionally repressed in adult tissues through promoter CpG methylation and suppressive histone modif...

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Detalhes bibliográficos
Main Authors: Li, Fang, Nellåker, Christoffer, Sabunciyan, Sarven, Yolken, Robert H., Jones-Brando, Lorraine, Johansson, Anne-Sofie, Owe-Larsson, Björn, Karlsson, Håkan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993755/
https://ncbi.nlm.nih.gov/pubmed/24478419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03628-13
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