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Activation of the Interferon Induction Cascade by Influenza A Viruses Requires Viral RNA Synthesis and Nuclear Export

We have examined the requirements for virus transcription and replication and thus the roles of input and progeny genomes in the generation of interferon (IFN)-inducing pathogen-associated molecular patterns (PAMPs) by influenza A viruses using inhibitors of these processes. Using IFN regulatory fac...

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Detalhes bibliográficos
Main Authors: Killip, Marian J., Smith, Matt, Jackson, David, Randall, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993719/
https://ncbi.nlm.nih.gov/pubmed/24478437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03109-13
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