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Activation of the Interferon Induction Cascade by Influenza A Viruses Requires Viral RNA Synthesis and Nuclear Export

We have examined the requirements for virus transcription and replication and thus the roles of input and progeny genomes in the generation of interferon (IFN)-inducing pathogen-associated molecular patterns (PAMPs) by influenza A viruses using inhibitors of these processes. Using IFN regulatory fac...

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Bibliografiska uppgifter
Huvudupphovsmän: Killip, Marian J., Smith, Matt, Jackson, David, Randall, Richard E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993719/
https://ncbi.nlm.nih.gov/pubmed/24478437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03109-13
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