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Beyond the Roche Ester: A New Approach to Polypropionate Stereotriad Synthesis

[Image: see text] An efficient, step-economical, and scalable approach to the synthesis of polypropionate stereotriads has been developed. Either 2-butyne or propyne is subjected to rhodium-catalyzed silylformylation and in situ crotylation of the resulting aldehydes. Tamao oxidation under either “s...

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Autori principali: Foley, Corinne N., Leighton, James L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993613/
https://ncbi.nlm.nih.gov/pubmed/24502345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol500051e
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