Attenuating Mutations in nsP1 Reveal Tissue-Specific Mechanisms for Control of Ross River Virus Infection

Ross River virus (RRV) is one of a group of mosquito-transmitted alphaviruses that cause debilitating, and often chronic, musculoskeletal disease in humans. Previously, we reported that replacement of the nonstructural protein 1 (nsP1) gene of the mouse-virulent RRV strain T48 with that from the mou...

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Hlavní autoři: Stoermer Burrack, Kristina A., Hawman, David W., Jupille, Henri J., Oko, Lauren, Minor, Marissa, Shives, Katherine D., Gunn, Bronwyn M., Long, Kristin M., Morrison, Thomas E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993543/
https://ncbi.nlm.nih.gov/pubmed/24429363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02609-13
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