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Interleukin-1 Receptor but Not Toll-Like Receptor 2 Is Essential for MyD88-Dependent Th17 Immunity to Coccidioides Infection

Interleukin-17A (IL-17A)-producing CD4(+) T helper (Th17) cells have been shown to be essential for defense against pulmonary infection with Coccidioides species. However, we have just begun to identify the required pattern recognition receptors and understand the signal pathways that lead to Th17 c...

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Detalhes bibliográficos
Main Authors: Hung, Chiung-Yu, Jiménez-Alzate, María del Pilar, Gonzalez, Angel, Wüthrich, Marcel, Klein, Bruce S., Cole, Garry T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993447/
https://ncbi.nlm.nih.gov/pubmed/24614655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01579-13
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