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Differential Requirement for PBP1a and PBP1b in In Vivo and In Vitro Fitness of Vibrio cholerae

We investigated the roles of the Vibrio cholerae high-molecular-weight bifunctional penicillin binding proteins, PBP1a and PBP1b, in the fitness of this enteric pathogen. Using a screen for synthetic lethality, we found that the V. cholerae PBP1a and PBP1b proteins, like their Escherichia coli homol...

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Main Authors: Dörr, Tobias, Möll, Andrea, Chao, Michael C., Cava, Felipe, Lam, Hubert, Davis, Brigid M., Waldor, Matthew K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993429/
https://ncbi.nlm.nih.gov/pubmed/24614657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00012-14
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