VgrG-5 Is a Burkholderia Type VI Secretion System-Exported Protein Required for Multinucleated Giant Cell Formation and Virulence

The type VI secretion system (T6SS) has emerged as a critical virulence factor for the group of closely related Burkholderia spp. that includes Burkholderia pseudomallei, B. mallei, and B. thailandensis. While the genomes of these bacteria, referred to as the Bptm group, appear to encode several T6S...

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Detalhes bibliográficos
Main Authors: Schwarz, Sandra, Singh, Pragya, Robertson, Johanna D., LeRoux, Michele, Skerrett, Shawn J., Goodlett, David R., West, T. Eoin, Mougous, Joseph D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993412/
https://ncbi.nlm.nih.gov/pubmed/24452686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01368-13
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