Serum-Mediated Activation of Macrophages Reflects TcVac2 Vaccine Efficacy against Chagas Disease

Chagas disease is endemic in Latin America and an emerging infectious disease in the United States. No effective treatments are available. The TcG1, TcG2, and TcG4 antigens are highly conserved in clinically relevant Trypanosoma cruzi isolates and are recognized by B and T cells in infected hosts. D...

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Bibliografske podrobnosti
Main Authors: Gupta, Shivali, Silva, Trevor S., Osizugbo, Jessica E., Tucker, Laura, Spratt, Heidi M., Garg, Nisha J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993374/
https://ncbi.nlm.nih.gov/pubmed/24421046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01186-13
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