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Serum-Mediated Activation of Macrophages Reflects TcVac2 Vaccine Efficacy against Chagas Disease

Chagas disease is endemic in Latin America and an emerging infectious disease in the United States. No effective treatments are available. The TcG1, TcG2, and TcG4 antigens are highly conserved in clinically relevant Trypanosoma cruzi isolates and are recognized by B and T cells in infected hosts. D...

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Hlavní autoři: Gupta, Shivali, Silva, Trevor S., Osizugbo, Jessica E., Tucker, Laura, Spratt, Heidi M., Garg, Nisha J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993374/
https://ncbi.nlm.nih.gov/pubmed/24421046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01186-13
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