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N-Acylated Derivatives of Sulfamethoxazole and Sulfafurazole Inhibit Intracellular Growth of Chlamydia trachomatis

Antibacterial compounds with novel modes of action are needed for management of bacterial infections. Here we describe a high-content screen of 9,800 compounds identifying acylated sulfonamides as novel growth inhibitors of the sexually transmitted pathogen Chlamydia trachomatis. The effect was bact...

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Detalhes bibliográficos
Main Authors: Marwaha, Sania, Uvell, Hanna, Salin, Olli, Lindgren, Anders E. G., Silver, Jim, Elofsson, Mikael, Gylfe, Åsa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993265/
https://ncbi.nlm.nih.gov/pubmed/24566180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02015-13
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