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Exposure to Ceftobiprole Is Associated with Microbiological Eradication and Clinical Cure in Patients with Nosocomial Pneumonia

The percentage of the dosing interval that the non-protein-bound plasma concentration is above the MIC (%fT>MIC) for cephalosporins has been shown to correlate with microbiological outcomes in preclinical studies. However, clinical data are scarce. Using data from a randomized double-blind phase...

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Autors principals: Muller, A. E., Punt, N., Mouton, J. W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993259/
https://ncbi.nlm.nih.gov/pubmed/24514085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02611-13
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