Inhibition by Cellular Vacuolar ATPase Impairs Human Papillomavirus Uncoating and Infection

Several viruses, including human papillomaviruses, depend on endosomal acidification for successful infection. Hence, the multisubunit enzyme vacuolar ATPase (V-ATPase), which is mainly responsible for endosome acidification in the cell, represents an attractive target for antiviral strategies. In t...

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Autori principali: Müller, Konstantin H., Spoden, Gilles A., Scheffer, Konstanze D., Brunnhöfer, Regina, De Brabander, Jef K., Maier, Martin E., Florin, Luise, Muller, Claude P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993236/
https://ncbi.nlm.nih.gov/pubmed/24614368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02284-13
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