Synthesis and Antifungal Activity In Vitro of Isoniazid Derivatives against Histoplasma capsulatum var. capsulatum

Histoplasmosis is a severe infection that affects millions of patients worldwide and is endemic in the Americas. Amphotericin B (AMB) and itraconazole are highly effective for the treatment of severe and milder forms of the disease, but AMB is toxic, and the bioavailability of itraconazole is errati...

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Главные авторы: de Aguiar Cordeiro, Rossana, de Farias Marques, Francisca Jakelyne, de Aguiar Cordeiro, Rebecca, da Silva, Marcos Reinaldo, Donato Maia Malaquias, Angela, Silva de Melo, Charlline Vládia, Mafezoli, Jair, Ferreira de Oliveira, Maria da Conceição, Nogueira Brilhante, Raimunda Sâmia, Gadelha Rocha, Marcos Fábio, Pinheiro Gomes Bandeira, Tereza de Jesus, Costa Sidrim, José Júlio
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
Предметы:
Susceptibility
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993233/
https://ncbi.nlm.nih.gov/pubmed/24514090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01654-13
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