The Emergence of Linezolid Resistance among Enterococci in Intestinal Microbiota of Treated Patients Is Unrelated to Individual Pharmacokinetic Characteristics

Linezolid is an antimicrobial agent for the treatment of multiresistant Gram-positive infections. We assessed the impact of linezolid on the microbiota and the emergence of resistance and investigated its relationship with plasma pharmacokinetics of the antibiotic. Twenty-eight patients were treated...

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Autori principali: Bourgeois-Nicolaos, N., Nguyen, T. T., Defrance, G., Massias, L., Alavoine, L., Lefort, A, Noel, V., Senneville, E., Doucet-Populaire, F., Mentré, F., Andremont, A., Duval, X.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Clinical Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993229/
https://ncbi.nlm.nih.gov/pubmed/24566182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02251-13
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