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Pulmonary Mycobacterium bovis BCG Vaccination Confers Dose-Dependent Superior Protection Compared to That of Subcutaneous Vaccination

Worldwide, the Mycobacterium bovis BCG vaccine is one of the most widely used vaccines. However, it appears to be ineffective in preventing pulmonary tuberculosis. Here, we show that pulmonary BCG vaccination of mice with a broad dose range provides superior protection against Mycobacterium tubercul...

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Detalhes bibliográficos
Main Authors: Aguilo, Nacho, Toledo, Ana Maria, Lopez-Roman, Eva Maria, Perez-Herran, Esther, Gormley, Eamonn, Rullas-Trincado, Joaquin, Angulo-Barturen, Iñigo, Martin, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993116/
https://ncbi.nlm.nih.gov/pubmed/24501340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00700-13
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