Pulmonary Mycobacterium bovis BCG Vaccination Confers Dose-Dependent Superior Protection Compared to That of Subcutaneous Vaccination

Worldwide, the Mycobacterium bovis BCG vaccine is one of the most widely used vaccines. However, it appears to be ineffective in preventing pulmonary tuberculosis. Here, we show that pulmonary BCG vaccination of mice with a broad dose range provides superior protection against Mycobacterium tubercul...

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Hlavní autoři: Aguilo, Nacho, Toledo, Ana Maria, Lopez-Roman, Eva Maria, Perez-Herran, Esther, Gormley, Eamonn, Rullas-Trincado, Joaquin, Angulo-Barturen, Iñigo, Martin, Carlos
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993116/
https://ncbi.nlm.nih.gov/pubmed/24501340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00700-13
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