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Sulindac and Sulindac Metabolites in Nipple Aspirate Fluid and Effect on Drug Targets in a Phase I Trial

Regular use of nonsteroidal anti-inflammatory drugs (NSAIDs) has been associated with reduced risk of breast cancer. Sulindac, a non-selective NSAID with both cyclooxygenase 2 (COX2) dependent and independent activities, is a candidate for breast chemoprevention. We conducted a Phase Ib trial in 30...

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Detalhes bibliográficos
Main Authors: Thompson, Patricia A., Hsu, Chiu-Hsieh, Green, Sylvan, Stopeck, Alison T., Johnson, Karen, Alberts, David S., Chow, H.-H. Sherry
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993089/
https://ncbi.nlm.nih.gov/pubmed/20051377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-09-0120
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