Reduced ABCB1 Expression and Activity in the Presence of Acrylic Copolymers

Purpose: P-glycoprotein (P-gp; ABCB1), an integral membrane protein in the apical surface of human intestinal epithelial cells, plays a crucial role in the intestinal transport and efflux leading to changes in the bioavailability of oral pharmaceutical compounds. This study was set to examine the po...

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Main Authors: Mohammadzadeh, Ramin, Baradaran, Behzad, Valizadeh, Hadi, Yousefi, Bahman, Zakeri-Milani, Parvin
Format: Artigo
Jezik:Inglês
Izdano: Tabriz University of Medical Sciences 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992956/
https://ncbi.nlm.nih.gov/pubmed/24754004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5681/apb.2014.032
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