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Antidepressant Efficacy of Ketamine in Treatment-Resistant Major Depression: A Two-Site Randomized Controlled Trial

OBJECTIVE: Ketamine, a glutamate N-methyl-d-aspartate (NMDA) receptor antagonist, has shown rapid antidepressant effects, but small study groups and inadequate control conditions in prior studies have precluded a definitive conclusion. The authors evaluated the rapid antidepressant efficacy of ketam...

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Autori principali: Murrough, James W., Iosifescu, Dan V., Chang, Lee C., Al Jurdi, Rayan K., Green, Charles M., Perez, Andrew M., Iqbal, Syed, Pillemer, Sarah, Foulkes, Alexandra, Shah, Asim, Charney, Dennis S., Mathew, Sanjay J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992936/
https://ncbi.nlm.nih.gov/pubmed/23982301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2013.13030392
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