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Computational tools and resources for metabolism-related property predictions. 1. Overview of publicly available (free and commercial) databases and software

Metabolism has been identified as a defining factor in drug development success or failure because of its impact on many aspects of drug pharmacology, including bioavailability, half-life and toxicity. In this article, we provide an outline and descriptions of the resources for metabolism-related pr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Peach, Megan L, Zakharov, Alexey V, Liu, Ruifeng, Pugliese, Angelo, Tawa, Gregory, Wallqvist, Anders, Nicklaus, Marc C
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992830/
https://ncbi.nlm.nih.gov/pubmed/23088273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.12.150
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