The Loss of Activating Transcription Factor 4 (ATF4) Reduces Bone Toughness and Fracture Toughness

Even though age-related changes to bone tissue affecting fracture risk are well characterized, only a few matrix-related factors have been identified as important to maintaining fracture resistance. As a gene critical to osteoblast differentiation, activating transcription factor 4 (ATF4) is possibl...

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Autori principali: Makowski, Alexander J., Uppuganti, Sasidhar, Waader, Sandra A., Whitehead, Jack M., Rowland, Barbara J., Granke, Mathilde, Mahadevan-Jansen, Anita, Yang, Xiangli, Nyman, Jeffry S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992706/
https://ncbi.nlm.nih.gov/pubmed/24509412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.01.021
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