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IL-15 adjuvanted multivalent vaccinia-based universal influenza vaccine requires CD4(+) T cells for heterosubtypic protection

Current influenza vaccines are ineffective against novel viruses and the source or the strain of the next outbreak of influenza is unpredictable; therefore, establishing universal immunity by vaccination to limit the impact of influenza remains a high priority. To meet this challenge, a novel vaccin...

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Detalhes bibliográficos
Main Authors: Valkenburg, Sophie A., Li, Olive T. W., Mak, Polly W. Y., Mok, Chris K. P., Nicholls, John M., Guan, Yi, Waldmann, Thomas A., Peiris, J. S. Malik, Perera, Liyanage P., Poon, Leo L. M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992686/
https://ncbi.nlm.nih.gov/pubmed/24706798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403684111
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