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Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo

Centrosomes are the microtubule-organizing centers of animal cells that organize interphase microtubules and mitotic spindles. Centrioles are the microtubule-based structures that organize centrosomes, and a defined set of proteins, including spindle assembly defective-4 (SAS4) (CPAP/CENPJ), is requ...

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Detalhes bibliográficos
Main Authors: Bazzi, Hisham, Anderson, Kathryn V.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992648/
https://ncbi.nlm.nih.gov/pubmed/24706806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400568111
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