Induced sputum and bronchial mucosal expression of interleukin-13 is not increased in chronic obstructive pulmonary disease

BACKGROUND: The Th2 cytokine interleukin-13 (IL-13) has been implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD). We sought to examine IL-13 expression in COPD subjects in induced sputum and bronchus specimens. We hypothesized that inflammatory cells expressing IL-13 local...

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Detalhes bibliográficos
Main Authors: Saha, S., Mistry, V., Siva, R., Parker, D., May, R., Bradding, P., Pavord, I. D., Brightling, C. E., Brightling, Christopher E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992380/
https://ncbi.nlm.nih.gov/pubmed/18699941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1398-9995.2008.01717.x
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