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Transgenic mice that overexpress the human trefoil peptide pS2 have an increased resistance to intestinal damage.

pS2 is a member of the trefoil peptide family, all of which are overexpressed at sites of gastrointestinal injury. We hypothesized that they are important in stimulating mucosal repair. To test this idea, we have produced a transgenic mice strain that expresses human pS2 (hpS2) specifically within t...

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Bibliographische Detailangaben
Hauptverfasser: Playford, R J, Marchbank, T, Goodlad, R A, Chinery, R A, Poulsom, R, Hanby, A M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC39923/
https://ncbi.nlm.nih.gov/pubmed/8700898
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