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Effects of Preoperative Hypoxia on White Matter Injury Associated with Cardiopulmonary Bypass in a Rodent Hypoxic and Brain Slice Model

BACKGROUND: White matter (WM) injury is common after cardiopulmonary bypass or deep hypothermic circulatory arrest (DHCA) in neonates who have cerebral immaturity secondary to in utero hypoxia. The mechanism remains unknown. We investigated effects of preoperative-hypoxia on DHCA-induced WM-injury u...

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Main Authors: Agematsu, Kota, Korotcova, Ludmila, Scafidi, Joseph, Gallo, Vittorio, Jonas, Richard A., Ishibashi, Nobuyuki
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992169/
https://ncbi.nlm.nih.gov/pubmed/24488087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2014.9
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