PML-nuclear bodies decrease with age and their stress response is impaired in aged individuals

BACKGROUND: Promyelocytic leukemia nuclear bodies (PML-NBs) have been depicted as structures which are involved in processing cell damages and DNA double-strand break repairs. The study was designed to evaluate differences in patients’ PML-NBs response to stress factors like a cancerous disease and...

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Detalhes bibliográficos
Main Authors: Wenger, Barbara, Schwegler, Manuela, Brunner, Maria, Daniel, Christoph, Schmidt, Manfred, Fietkau, Rainer, Distel, Luitpold V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992156/
https://ncbi.nlm.nih.gov/pubmed/24694011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2318-14-42
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