Hypoxia in Melanoma: Using Optical Spectroscopy and EF5 to Assess Tumor Oxygenation Before and During Regional Chemotherapy for Melanoma

BACKGROUND: There is increasing evidence that tumor hypoxia plays a significant role in the chemoresistance of melanoma, but to our knowledge, real-time tumor oxygenation during isolated limb infusion (ILI) has not been studied. We sought to demonstrate the feasibility of measuring real-time alterat...

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Main Authors: Speicher, Paul J., Beasley, Georgia M., Jiang, Belly, Lidsky, Michael E., Palmer, Gregory M., Scarbrough, Peter M., Mosca, Paul J., Dewhirst, Mark W., Tyler, Douglas S.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992126/
https://ncbi.nlm.nih.gov/pubmed/23982250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-013-3222-0
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