Study protocol of the RAND-study: a multicenter, prospective cohort study investigating response and adherence to nilotinib treatment in chronic myeloid leukemia

BACKGROUND: The antitumor drug nilotinib has a large inter- and intra individual variability in pharmacokinetics. Adherence to treatment may substantially influence plasma levels and has been recognized as the most important determinant of treatment failure in chronic myeloid leukemia (CML). A bette...

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Detalhes bibliográficos
Main Authors: Boons, Christel CLM, Swart, Eleonora L, Timmers, Lonneke, van de Ven, Peter M, Janssen, Jeroen JWM, Hugtenburg, Jacqueline G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991921/
https://ncbi.nlm.nih.gov/pubmed/24712728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-247
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