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Interpreting Frequency Responses to Dose-Conserved Pulsatile Input Signals in Simple Cell Signaling Motifs

Many hormones are released in pulsatile patterns. This pattern can be modified, for instance by changing pulse frequency, to encode relevant physiological information. Often other properties of the pulse pattern will also change with frequency. How do signaling pathways of cells targeted by these ho...

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Detalhes bibliográficos
Main Authors: Fletcher, Patrick A., Clément, Frédérique, Vidal, Alexandre, Tabak, Joel, Bertram, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991699/
https://ncbi.nlm.nih.gov/pubmed/24748217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095613
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