IFNL4 ss469415590 Variant Shows Similar Performance to rs12979860 as Predictor of Response to Treatment against Hepatitis C Virus Genotype 1 or 4 in Caucasians

OBJECTIVES: The rs12979860 variant, linked to IL28B gene, predicts sustained viral response (SVR) to pegylated-interferon/ribavirin (pegIFN/RBV) therapy in Hepatitis C Virus genotype 1 or 4 (HCV-1/4)-infected patients. Recently, a functional variant, ss469415590, in linkage disequilibrium (LD) with...

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Detalhes bibliográficos
Main Authors: Real, Luis M., Neukam, Karin, Herrero, Rocío, Guardiola, Josep M., Reiberger, Thomas, Rivero-Juarez, Antonio, Salazar, Juliana, Mandorfer, Mattias, Merino, Dolores, Soriano, Vicente, Rivero, Antonio, Macías, Juan, Pineda, Juan A., Caruz, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991683/
https://ncbi.nlm.nih.gov/pubmed/24748394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095515
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