Oxidative Stress Induced Mitochondrial Failure and Vascular Hypoperfusion as a Key Initiator for the Development of Alzheimer Disease

Mitochondrial dysfunction may be a principal underlying event in aging, including age-associated brain degeneration. Mitochondria provide energy for basic metabolic processes. Their decay with age impairs cellular metabolism and leads to a decline of cellular function. Alzheimer disease (AD) and cer...

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Main Authors: Aliev, Gjumrakch, Palacios, Hector H., Gasimov, Eldar, Obrenovich, Mark E., Morales, Ludis, Leszek, Jerzy, Bragin, Valentin, Herrera, Arturo Solís, Gokhman, Dmitry
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Diversity Preservation International 2010
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Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991025/
https://ncbi.nlm.nih.gov/pubmed/27713247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph3010158
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