The Missense of Smell: Functional Variability in the Human Odorant Receptor Repertoire

Humans have approximately 400 intact odorant receptors, but each individual has a unique set of genetic variations that lead to variation in olfactory perception. We used a heterologous assay to determine how often genetic polymorphisms in odorant receptors alter receptor function. We identified ago...

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Detalhes bibliográficos
Main Authors: Mainland, Joel D., Keller, Andreas, Li, Yun R., Zhou, Ting, Trimmer, Casey, Snyder, Lindsey L., Moberly, Andrew H., Adipietro, Kaylin A., Liu, Wen Ling L., Zhuang, Hanyi, Zhan, Senmiao, Lee, Somin S., Lin, Abigail, Matsunami, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990440/
https://ncbi.nlm.nih.gov/pubmed/24316890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3598
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