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The Missense of Smell: Functional Variability in the Human Odorant Receptor Repertoire

Humans have approximately 400 intact odorant receptors, but each individual has a unique set of genetic variations that lead to variation in olfactory perception. We used a heterologous assay to determine how often genetic polymorphisms in odorant receptors alter receptor function. We identified ago...

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Bibliografische gegevens
Hoofdauteurs: Mainland, Joel D., Keller, Andreas, Li, Yun R., Zhou, Ting, Trimmer, Casey, Snyder, Lindsey L., Moberly, Andrew H., Adipietro, Kaylin A., Liu, Wen Ling L., Zhuang, Hanyi, Zhan, Senmiao, Lee, Somin S., Lin, Abigail, Matsunami, Hiroaki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990440/
https://ncbi.nlm.nih.gov/pubmed/24316890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3598
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