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Molecular mechanism and physiological role of active–deactive transition of mitochondrial complex I

The unique feature of mitochondrial complex I is the so-called A/D transition (active–deactive transition). The A-form catalyses rapid oxidation of NADH by ubiquinone (k ~10(4) min(−1)) and spontaneously converts into the D-form if the enzyme is idle at physiological temperatures. Such deactivation...

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Detalhes bibliográficos
Main Authors: Babot, Marion, Galkin, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990385/
https://ncbi.nlm.nih.gov/pubmed/24059527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20130088
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